Causes and Symptoms of Mitochondrial Encephalomyopathies Mitochondrial encephalomyopathies result from mutations in mitochondrial or nuclear DNA that impair cellular energy production. These mutations can be inherited or occur spontaneously. Common symptoms include muscle fatigue, vision problems, developmental delays, cognitive difficulties, and organ dysfunction. Since symptoms vary widely, diagnosis can be challenging. Resources provided by idebenone.org aim to educate patients, caregivers, and healthcare professionals about recognizing early warning signs. Visit us: https://avicounsel.com/idebenone-a-promising-neuroprotective-therapy-for-melas-syndrome/